已证实内毒素水平超低
淋巴细胞分离液 (LSM) 可用于在体外从稀释的全血中进行淋巴细胞的分离。其分离原理为密度梯度离心，利用全血中不同细胞类型比重的差异通过离心完成细胞的分离 (图1)。康宁 cellgro®淋巴分离液是一种无菌的等渗聚蔗糖和泛影酸钠溶液，粘度低，在20℃下密度为1.077-1.080g/mL。
除了两种现成的LSM产品，康宁可以根据您的需求，提供不同体积和包装的产品定制。
特点
在FDA注册的，经ISO13485:2003质量认证的cGMP车间进行生产
依据SAL 10 的水平无菌过滤，高质量标准
超低内毒素浓度 (＜0.25EU/ml@1:10稀释）
众多文献引用
可定制不同规格
图1：全血在LSM中离心后的各类细胞分布
订购信息
参考文献
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2. Ability of Mature Dendritic Cells to Interact with Regulatory T Cells Is Imprinted during Maturation. R Muthuswamy et. al., Cancer Res July 15, 200868; 5972
3. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Natasa Obermajer et. al., Blood, Nov 2011; 118: 5498 - 5505.
4. Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy. Julia K. Tietze et.al, Blood, Mar 2012; 119: 3073 - 3083.
5. HLA-DR+ CD38+ CD4+ T Lymphocytes Have Elevated CCR5 Expression and Produce the Majority of R5-Tropic HIV-1 RNA In Vivo. Amie L. Meditzet. al., J.Virol., Oct 2011; 85: 10189 - 10200.
6. A Stimulation-Dependent Alternate Core Promoter Links Lymphotoxin α Expression with TGF-β1 and Fibroblast Growth Factor-7 Signaling in Primary Human T Cells. Brian H. Yokley et. al., J. Immunol., May 2013; 190: 4573 – 4584
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